Santillán’s work insinuates the existence of a territory where what is possible can be trespassed; where the invisible can be truthfully materialized, and where history is a speculative matter. It can be understood as an investigation of the margins of reality.

“Fiction here (in Santillán’s work) is employed as a tool, or a method, to transform reality into something, anything else – especially that which it could not be according to other disciplines such as science or logics or economy or politics – by inscribing it in an alternate historical narrative (...). Its purpose is to offer glimpses of alternative possibilities and possible alternatives by altering our standard historiographies and, hence, broaden our roadmaps.” Timotheus Vermeulen and Robin van den Akker, co-founders of Notes on Metamodernism.

Santillán received a Sculpture MFA from VCU (US), and attended residencies at Delfina Foundation (UK), Jan van Eyck (NL), Skowhegan (US), Fondazione Ratti (IT), Davidoff AIR (DO), among others. 

His work has been displayed at Witte de With (NL), LACMA (US), MUAC (MX), Irish Museum of Modern Art (IE), IV Poligraphic Triennial (PR), Museo de Arte ‘Carrillo Gil’ (MX), STUK (BE), Fundación ODEON (CO), SECCA (US), Passerelle Centre d’art contemporain (FR), Nest (NL), Sala Miró Quesada (PE), FLORA ars+natura (CO), Bonnefanten Museum (NL), XIII Bienal de Cuenca (EC), Kröller-Müller Museum (NL), Bienal de Arte Paíz (GT), Voorlinden Museum (NL), among other venues. And, Santillan’s work has been the subject of articles, reviews, and interviews published on Frieze magazine, Art Pulse, Elephant, Art Nexus, Art Monthly, Exibart, Metropolis M, among others.